Review of AddieUP – Does the supplement with the provocative name live up to the hype?

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All of us have probably heard of the pharmaceutical drug Adderall.  It is the well known psycho-stimulant prescribed to sufferers of attention deficit hyperactive disorder (ADHD) and narcolepsy.IMG_3433

Unsurprisingly Adderall has also risen in popularity with student and hard charging populations who are seeking to improve their performance and cognitive faculties.

Unfortunately for many individuals Adderall can be dual-edged sword.  On the one hand there are those stimulatory positive effects already mentioned, but prolonged use or abuse can lead to an impairment in cognitive function, addiction, and a variety of potential physical ailments.

And so begins the back story to AddieUp. 

As promoted on the AddieUp website –

A doctor, who has experienced ADHD like symptoms since his childhood, frustrated by the negative and downside effects of Adderall (and Adderall like medications) decides to put together his own curated blend of ingredients to help himself and others consumers like him improve their focus, attention, and energy. 

Fast forward to today and – 

“AddieUP has been accepted worldwide as THE supplement that gives you FOCUSED ATTENTION, memory support, and INCREDIBLE LONG LASTING ENERGY”. 

The folks at AddieUP were kind enough to send over a sample to the Trading Edge to undergo one of our critical reviews.

In the following writeup we will review the ingredients in AddieUp, detail my own experience with the product, and finally give it rating based on the following 3 point criteria – quality of ingredients, nootropic effect, and value.


Ingredients list

First off let’s begin with the ingredients, stack ranked by quantity as per the label on the back of the bottle.


4-Amino-2-Methylpentane Citrate

4-Amino-2-Methylpentane Citrate (known as AMP Citrate) is a fairly new chemical and a popular product in the bodybuilding community. AMP Citrate was introduced widely after the banning of the infamous DMAA (1,3-dimethylamylamine) and has many similarities in function.  Note it’s so similar in fact that it does carry the same potential negative effects and potential health risks. AMP Citrate is a strong CNS stimulant that will help in increasing metabolism and energy.


Guarana – the guarana plant is a strong source of caffeine and generally consumed for its stimulatory effects.

Caffeine Anhydrous – this ingredient is the same caffeine we all know and love with the small difference being that in its anhydrous form it contains virtually no water, ie. less than 0.5%, and logic dictates that it would be more effective by relative weight.

Yerba Mate is a popular alternative caffeine source to coffee. This plant is a natural source of caffeine, but is noted for producing a smooth and stable boost in energy.  Yerba Mate is often considered a mild nootropic for increased alertness, improved mood, and heightened cognitive function.

PEA (Beta-Phenylethylamine) – The major benefits related to this supplement are mood enhancement and an overall feeling of well being. Due to the release of circulating levels of dopamine and acetylcholine it is even possible that some users may experience a feeling akin to a natural “high.”

It has also been noted that supplementation with Beta Phenylethylamine may help to reduce stress and even help reduce symptoms associated with ADD and ADHD (those who suffer with these conditions typically have low levels of Phenylethylamine in their systems).

Norcoclaurine HCl / Higenamine – another powerful stimulant known to promote fat loss by inducing lipolysis.  Higenamine has been shown to enhance vasodilation and vascular relaxation.

Methyl-Synephrine HCL

A popular stimulant used as an alternative to Ephedrine. It is commonly used for weight and fat loss by increasing metabolic rate purportedly without an increase in heart rate.   

Choline Bitartrate Choline is an essential nutrient found commonly in foods like eggs.  Choline Bitartrate is popular form of choline where a simple salt is tacked on to improve absorption. 

Ginkgo Biloba – is a well known adaptogen most notable known for its ability to improve short term memory and free recall, especially in older adults affected by cognitive decline. 

Ginkgo has also been shown to boost mood and reduce stress and anxiety by being able to reduce corticosterone, which is the hormone that regulates how you respond to stress.

Huperzine A – The most well known benefits of Huperzine A include enhancing memory and learning skills. Studies show that Huperzine A increases acetylcholine in the body by preventing its breakdown by the enzyme acetylcholinesterase.

4 day experiment

As posted on AddieUP’s website, the company website recommends taking between 1-2 pills / day.test_tube

AddieUP sent over 4 pills so the plan was to take 1 pill a day for 4 days and evaluate it based on the following 3 criteria – quality of ingredients, nootropic effect, and value.

Day 1 – Monday

After a fast from coffee over the weekend I was ready for a little stimulation to start my Monday.

I took 1 AddieUP and within approximately 20 minutes I started to feel some very noticeable effects.

For the better part of the morning I would best describe my state as being slightly edgy but very communicative. 

Qualitatively verbal fluency seemed improved and I found myself with high levels of energy, focused and extremely talkative, more so than usual.

At one point I remarked to myself that I definitely felt like I was on “something”.  This is a feeling that I could see some people either enjoying or not enjoying. [Tweet “At one point I remarked to myself that I definitely felt like I was on “something”. This is a feeling that I could see some people either enjoying or not enjoying. “]

By lunchtime the effects had dissipated and I felt no major crash or any difficulty falling asleep later that night.

Chalk day 1 up to a fairly decent experience and a good start.

Day 2 – Tuesday

On the 2nd day of the experiment, as I’ve done in previous nootropic reviews, I elected to stack AddieUP with BulletProof Coffee (BPC). 

As listed on AddieUP’s website, each AddieUP pill contains up to 100 grams of caffeine (or basically a strong cup of coffee). 

Generally I take my BPC with L-theanine and the combination gives me very good focus and long lasting energy.

I am fairly tolerant to caffeine so was interested in how they would stack.

I started with 1 AddieUP pill at 830am and 1 hour later I proceeded to take my BPC. 

Interestingly on this day, in the hour between the AddieUP and the BPC, I felt next to no effects from the AddieUP which was a marked contrast from the day before.

By the time to BPC started to kick in it voided any and all noticeable effects of the AddieUP.

By mid-afternoon I was very tired and in dire need of another pick up or nap.

Day 3 – Wednesday

With only 2 pills left I was curious to continue to explore how AddieUP would stack with other nootropics.

So Day 3 started with CILTEP upon waking followed by AddieUP approximately 1.5 hours later.

As remarked on Day 1, I noticed an increase in verbal fluency as well as very good energy however the focus was not as sharp.

I found myself getting easily distracted and having to recenter and refocus myself on the task at hand at various times throughout the day.  Once refocused I had good energy and managed to get through my to-do list.

Day 4 – Thursday

Finally Day 4 on the experiment, time to add a classic racetam to the stack.

Started the day with CILTEP at 8am, and followed that up with AddieUP at 9am and 2.4g of Piracetam 15 minutes later.

As in Day 3 the effects of AddieUP were very subtle, if any.  However the combination of the three gave me plenty of focus and and I easily plowed through my day’s tasks while also taking on several new projects. 

Conclusion and takeaways

So how did AddieUp stack up on our three point scale (with 1 being the worst and 10 being the best) –

Quality of ingredients – 3

Interestingly in a previous blend of AddieUP 1, 3 dimethylamylamine – Also known as Methylhexanmine or DMAA – had been one of the main active ingredients.  Upon perusing various sites online I found many reviewers mention they had preferred the previous formulation over the current formulation without DMAA.

In its current formulation AddieUP is pretty much all energy pill with very few nootropic ingredients or properties.   Even though Caffeine is listed as being less than 9% of the overall volume of the ingredients, 7 out of the 10 ingredients were a mish mash of stimulants.

Many of the same ingredients are also very popular among the bodybuilding community for the purposes of weight loss and maintenance so it’s curious to see AddieUP also marketing themselves as a weight loss supplement.

The choline in the form of choline bitartrate is also on the lower end of choline sources with Alpha-GPC being my preferred source.


Also I’ve never been a fan of “black box” blends.  I understand that AddieUP has every right to protect the blend of their product but as a consumer I would like the transparency of understanding the quantities of the ingredients on the label before ingesting them.

Nootropic effect – 3

Other than Day 1 of my trial I can’t say that AddieUP was especially effective.

Others have also reported that they quickly gained a tolerance to AddieUP and even though my trial was very short it was hard to say that I felt any effects after the 1st day. 

To be fair I did stack AddieUP with (or against depending how you see things) various nootropics that could have on the one hand masked the effects of AddieUP or on the other hand  were more effective than AddieUP.

However from a pure nootropics perspective AddieUP simply doesn’t contain enough nootropic ingredients to be labelled a nootropic stack. 

Rather it is a blend intended more for it’s stimulative properties, and perhaps even weight loss properties, than a true non-stimulatory cognitive enhancement.  

Value – 7

At the time of this review I was able to find a 60 pill bottle of AddieUP for $50 which works out to approximately $0.83 per pill. 

That basically comes in under a small cup of McDonalds coffee which retails for a $1.

So bang for your buck that’s not bad value.

Overall and summary – 4.3

AddieUP markets itself as a supplement that can give energy, focus, and memory support.  So do they deliver?

Technically I believe they deliver on all of those claims however I’m not particularly impressed on its effectiveness and I have some reservations around how effective this supplement would be over time as I could see tolerance becoming an issue very quickly.

There are many more points I could debate but the ultimate question is would I consider using this product on a regular basis? 

Truthfully the answer is no.   

Energy pills are not my cup of tea (pardon the mixed metaphors) and if I needed a morning kick I would personally prefer a cup of BPC over an energy pill.


Review of AddieUP – Does the supplement with the provocative name live up to the hype?

by editor time to read: 7 min